name :MGF (Mechano growthfactor) (IGF- IEC)
specification: 2mg/vial, 10vials/box
MGF (also known as IGF-1Ec) is a splice variant of the IGF gene which increases stem cell count in the muscle and allows for muscle fibers to fuse and mature. This is a process required for the growth of adult muscle. MGF is produced naturally when muscle fibers are broken down through resistance (weight training). MGF stimulates muscle growth, creates new muscle fibers, promotes muscle recovery, promotes nitrogen retention and increases protein synthesis.
In studies where MGF was administered intramuscularly, there was a 20% increase in the weight of the injected muscle fibers within 2 weeks. In further studies, it took 4 months for IGF to cause a 25% increase in muscle mass. MGF was found to be more potent than IGF-1 in rapid muscle growth. Fat loss and strength increases are not typically seen with MGF’s use (as they are with IGF-1 use).
MGF is a prime candidate for gene doping for enhancement of athletic performance. MGF can produce rapid increases in muscle and strength, giving it considerable therapeutic and doping potential. Its potential for optimising physical training.
Let's start with an explanation of Mechano Growth Factor (MGF) and what it does. The muscle insulin-like growth factor-I (IGF-I) mRNA splice variant (IGF-IEc) has been identified in rodents. IGF-IEc, also called mechano growth factor (MGF) has been found to be up-regulated by exercise or muscle damage. Growth hormone (GH) is the principal regulator of IGF-I expression in several tissues including the skeletal muscle.
MGF is derived from IGF-I but its sequence differs from the systemic IGF-I produced by the liver. MGF is expressed by mechanically overloaded muscle and is involved in tissue repair and adaptation. It is expressed as a pulse following muscle damage and is apparently involved in the activation of muscle satellite (stem) cells. These donate nuclei to the muscle fibres that are required for repair and for the hypertrophy processes which may have similar regulatory mechanisms.
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Loss of muscle mass in old age and in certain diseases is associated with an impaired ability to express MGF.
- The ability to produce MGF declines with age, and this is commensurate with the decline in circulating GH levels.
- MGF has been shown to boost muscle mass by improving the ability of wasted tissue to grow.
- MGF has been shown to improve the ability of wasted tissue to grow.
- MGF has been shown to activate muscle stem cells.
- MGF has been shown to increase the upregulation of protein synthesis.
- MGF induces rapid muscle hypertrophy.
- MGF has considerable potential as a generic means of treating muscle cachexia.
- Mechano Factor (MGF) targets skeletal tissue, and promotes muscle growth by repairing the damaged tissue and upregulating protein synthesis.
When you train, what happens to your muscles is they break down, the cells are damaged, muscle tissue needs to be repaired and your body produces 2 forms of MGF splice variant. The first initial release of the above mentioned number 1 variant from the liver helps muscle cell recovery, if there is no MGF then muscle cells die.
As muscle is a post-mitotic tissue and as such cell replacement is not a means of tissue repair, if the cells are not repaired they die and your muscles get smaller and weaker. In muscle tissue, the pool of these stem cells is apparently replenished by the action of MGF, which is produced as a pulse following damage.
Now, with synthetic injections of MGF you can increase the pulse and so speed up recovery, and increase the muscle tissue cells by stimulating satellite cells into full maturity. In terms of dosages, 200mcg bi-laterally is the very best choice of dosing in muscles trained.
MGF, short for Mechano Growth Factor is one of the most recent craze in the bodybuilding community. It has been used by bodybuilders, athletes and sportsmen alike due to its purported anabolic effects which promotes increased muscle mass, lean muscles, physical performance and fat loss. This profile overview are the things that you must know before purchasing or using MGF.
Despite its anabolic activity, many people prefer PEG MGF than buying MGF. This is so as MGF has very short half-life lasting with 5 to 7 minutes only. Moreover, it should be used immediately after workout or physical activities as it wouldn't work with an undamaged muscle tissue. Still, it may be an effective treatment for individuals suffering from muscle wasting medical conditions.
MGF was first discovered by a group of researchers in the human muscle. It is also known as IGF-1Ec. MGF is a repair factor or growth factor that is derived from a muscle tissue that has been damaged or injured. It is also found on exercised muscle tissues.
Compared to other IGF variants, MGF is very special because of its role in muscle growth and development. Research and anecdotal evidence has shown that it is able to help with the regrowth and improvement of wasted or atrophied tissues through increasing the regulation of protein synthesis and activating the stem cells found in the muscles. Its exceptional ability to help in muscle regrowth can help in lessening speed of recovery whilst increase muscle growth.
Furthermore, MGF is able to activate stem cells through initiating muscle satellite cell activation alongside its ability to improve its IGF-1 receptor activities. As a direct result, MGF is able to improve turnover of protein synthesis. Hence, if MGF is used efficiently and correctly, it could greatly help in increasing muscle mass over time.
Before explaining how synthetic MGF works, you must know that the liver naturally produces two types of MGF splice variants. The first one is IGF-1Ec. IGF-1Ec stimulates your satellite cells to be activated and it is considered to be the closest IGF variant of the synthetic MGF. The second MGF splice variant is IGF-1Ea. Compared to IGF-1Ec, IGF-1Ea is far less anabolic.
Synthetic MGF only works in the body after the introduction of mechanical overload towards your muscles (e.g. after weight training or heavy workouts). When your muscle is subjected to exercise or injury, IGF-1 gene is released which is then spliced as an immediate response of your body. Primarily, the early splicing stimulates the activation of satellite cells allowing the stimulation of undamaged cells to grow new muscle tissues and fibers. The presence of MGF also helps with the upregulation of protein synthesis. After which, systemic release of IGF-1Ea from your liver occurs - a process that also helps with the upregulation of protein synthesis within your body. Simply put it, the primary anabolic mechanism of MGF is related to the release of IGF-1 splice variants during muscle regrowth and healing.
| Product Name: | MGF |
| Unit size: | 2 mg/vial |
| CAS NO.: | 62031-54-3 |
| Synonyms: | MGF, Mechano Growth Facto*, |
| Sequence: | Tyr-Gln-Pro-Pro-Ser-Thr-Asn-Lys-Asn-Thr-Lys-Ser-Gln-Arg-Arg-Lys-Gly-Ser-Thr-Phe-Glu-Glu-Arg-Lys |
| Purity: | ≥99% (HPLC) |
| Physical State: | Lyophilized Powder |
| Solubility: | Soluble in water or 1% acetic acid |
| Storage: | Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18°C. Upon reconstitution of the peptide it should be stored at 4°C between 2-21 days and for future use below -18°C. |
HPLC Report:>98.59%
MS Report
Training, bodybuilding and extreme physical activities causes muscle breakdown and muscle tissue & cells damage. Note that human muscles are post-mitotic tissues, hence, cell replacement is not a viable option for tissue repair. If your body is unable to repair your damaged muscle cells, they die leading to weaker and smaller muscles. Apparently, MGF is able to stimulate muscle regrowth and development.
Injection of synthetic MGF could help increase the speed of your recovery from muscle injury. It could also increase your muscle cells through stimulating your satellite cells into maturity. To achieve this, you must use MGF in proper dosages and as recommended by manufacturers.
1.For products exported we can offer COA Certificate and official PI.
2.We are manufacturer with own lab and factory, can provide high quality products with factory price.
3.Products can be sent out in 24 hours after payment. Tracking number available, fixed service person are 7x24h for you to contact.
4.Secure and discreet shipment. Various transportation methods for your choice, like DHL/UPS/TNT/FedEx/SF-express.
5.Customs pass and satisfied rate ≥99%.
6.For hot sale products we have stock in there for transferring.
7.Products purity is test by our quality department strictly before sending, and you can askthe third testing organization come and inspect, such as (SGS/ CTI/ ITS),
only after our confirmation will we send it out to you.
8.We have different couriers to different countries.
9.We have clients throughout the world.
Q1: Have your Product Quality been Approved by Third Party Lab？
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us.
Q2:How do you treat quality complaint？
A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC , TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem ,caused by us, we will send you free goods for replacement or refund your loss.
Q3: Is there any discount？
A: Yes, for larger quantity, we always support with better price.
Q4:How long does it take to the goods arrived？
A:It is Depending on your location.
Q5 Do you have any reshipment policy？
A: We have good after-sale service and re-shipment policy if the parcel lose. Our long association with our clients has brought great benefits. We always take the upmost care in the packaging of our products . Our clients will confirm this as even they struggle to find them without help at times. But in spite of our best efforts it is still possible will seize a small number of packages.
In this circumstance we promise reship free to establish long term relationship.
1. High purity and good quality.
2. Professional and discreet packing.
3. Fast and safe delivery.
4. High success rate to pass customs.
1. All products will have been strictly Quality Checked in house before pecking.
2. All products will be well packed before shipping.
3. Parcel can be sent out in 24 hours after payment.Tracking number available
4. Secure and discreet shipment.Various transportation methods for your choice.
5. Customs pass rate ≥99%
6. We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.
|
Product Name |
Specification |
Product Name |
Specification |
|
MGF |
2mg/vial |
CJC-1295 with DAC |
2mg/vial |
|
PEG MGF |
2mg/vial |
CJC-1295 without DAC |
2mg/vial |
|
PT-141 |
10mg/vial |
MT-1 |
10mg/vial |
|
Ipamorelin |
2mg/5mg/vial |
MT-2 |
5mg/10mg/vial |
|
GHRP-2 |
5mg/10mg/vial |
GHRP-6 |
5mg/10mg/vial |
|
Hexarelin |
2mg/vial |
Oxytocin |
2mg/vial |
|
Sermorelin |
2mg/vial |
TB500 |
2mg/vial |
|
Pentadecapeptide BPC 157 |
2mg/vial |
Triptorelin |
2mg/vial |
|
Fragment 176-191 |
2mg/vial |
Tesamorelin |
2mg/vial |
|
Fragment 176-191 |
5mg/vial |
Selank |
5mg/vial |
|
Fragment 176-191 |
10mg/vial |
Follistatin 344 |
1mg/vial |
|
Gonadorelin |
2mg/vial |
Follistatin 315 |
1mg/vial |
|
DSIP |
2mg/vial |
Epitalon |
10mg/vial |
|
AOD-9604 |
2mg/vial |
Adipotide |
2mg/vial |
|
ACE 031 |
1mg/vial |
GDF-8 |
1mg/vial |
Q1: Have your Product Quality been Approved by Third Party Lab?
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us.
Q2:How do you treat quality complaint?
A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC , TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem , caused by us, we will send you free goods for replacement or refund your loss.
Q3: Do you Accept Sample Order?
A: Yes, we accept small order from 10g, 100g and 1kg for your evaluation quality of our goods.
Q4: Is there any discount?
A: Yes, for larger quantity, we always support with better price.
Q5:Do you accept VISA business credit card ?
A:Sorry we don't accept VISA credit card,
We'd like to accept bank transfer, or Paypal or Moneygram
Q6:How long does it take to the goods arrived ?
A:It is Depending on your location,
For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.
For mass order, please allow 5-8 days by Air, 20-35 days by Sea.
Q7. Do you have any reshipment policy ?
we have good after-sale service and re-shipment policy if the parcel lose
Our long association with our clients has brought great benefits
We always take the upmost care in the packaging of our products
our clients will confirm this as even they struggle to find them without help at times.
But in spite of our best efforts it is still possible will seize a small number of packages.
In this circumstance we promise reship free to establish long term relationship
Q8 :Can I get a sample?
A: Of course. For most products we can provide you a free sample, while the shipping cost should
undertake by your side.
As a leading manufacturer of steroid raw materials,and Peptides
We specialized in manufacturing high quality and reliable raw material
which are widely used in the fields of food, health, cosmetics, pharmaceuticals, and Bodybuilding
we have formed a technology and management team that cooperate closely with some overseas Labs all speak highly of our safe shipping and goods .
please do not hesitate to contact us.
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